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The VIP Study will include pregnant women over 18 years of age with type 1, type 2, or type 3 von Willebrand disease. Women with type 1 von Willebrand disease can only take part in the study if their levels of VWF are below 30% of the normal level.

To take part in the study, women will need to provide consent in writing before week 39 of pregnancy.

Women with any of the following conditions are NOT allowed to take part in the study:

  • A disorder of hemostasis, platelet dysfunction, or collagen disorder other than von Willebrand disease
  • Liver disease
  • Renal disease
  • Preeclampsia or eclampsia
  • HELLP syndrome (hemolysis, elevated liver enzymes, and a low platelet count)
  • Thrombotic thrombocytopenic purpura (TTP)
  • Disseminated intravascular coagulation (DIC)
  • Any other acquired vasculopathy or coagulopathy